Invention Grant
- Patent Title: Ether benzotriazole derivatives
- Patent Title (中): 醚苯并三唑衍生物
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Application No.: US13247009Application Date: 2011-09-28
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Publication No.: US08785481B2Publication Date: 2014-07-22
- Inventor: Douglas C. Beshore , Vadim Dudkin , Robert M. Garbaccio , Adam W. Johnson , Scott D. Kuduk , Jason W. Skudlarek , Cheng Wang , Mark E. Fraley
- Applicant: Douglas C. Beshore , Vadim Dudkin , Robert M. Garbaccio , Adam W. Johnson , Scott D. Kuduk , Jason W. Skudlarek , Cheng Wang , Mark E. Fraley
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Keith D. MacMillan; John C. Todaro
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; C07D249/04
Abstract:
The present invention is directed to ether benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
Public/Granted literature
- US20120135977A1 ETHER BENZOTRIAZOLE DERIVATIVES Public/Granted day:2012-05-31
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