Invention Grant
US08790648B2 Methods of treating psoriasis using IL-17 receptor A antibodies
有权
使用IL-17受体A抗体治疗牛皮癣的方法
- Patent Title: Methods of treating psoriasis using IL-17 receptor A antibodies
- Patent Title (中): 使用IL-17受体A抗体治疗牛皮癣的方法
-
Application No.: US13472074Application Date: 2012-05-15
-
Publication No.: US08790648B2Publication Date: 2014-07-29
- Inventor: Joel Tocker , Jacques J. Peschon , David Fitzpatrick , James F. Smothers , Christopher Mehlin , Ai Ching Lim
- Applicant: Joel Tocker , Jacques J. Peschon , David Fitzpatrick , James F. Smothers , Christopher Mehlin , Ai Ching Lim
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61P17/06 ; C12N15/13 ; C12N15/85
Abstract:
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
Public/Granted literature
- US20120251547A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS Public/Granted day:2012-10-04
Information query
