Invention Grant
- Patent Title: Stable pharmaceutical composition containing docetaxel and a method of manufacturing the same
- Patent Title (中): 含有多西紫杉醇的稳定的药物组合物及其制造方法
-
Application No.: US12301700Application Date: 2007-05-22
-
Publication No.: US08791152B2Publication Date: 2014-07-29
- Inventor: Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
- Applicant: Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
- Applicant Address: KR Gyeonggi-Do
- Assignee: SK Chemicals Co., Ltd.
- Current Assignee: SK Chemicals Co., Ltd.
- Current Assignee Address: KR Gyeonggi-Do
- Agency: Frommer Lawrence & Haug LLP
- Agent Ronald R Santucci
- Priority: KR10-2006-0045715 20060522; KR10-2007-0049340 20070521
- International Application: PCT/KR2007/002479 WO 20070522
- International Announcement: WO2007/136219 WO 20071129
- Main IPC: A61K31/335
- IPC: A61K31/335
Abstract:
The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
Public/Granted literature
- US20090163574A1 Stable Pharmaceutical Composition Containing Docetaxel and a Method of Manufacturing the Same Public/Granted day:2009-06-25
Information query
