Invention Grant
US08791300B2 Process for preparing a substituted dimethyl-(3-arylbutyl)amine compound by homogeneous catalysis
有权
通过均相催化制备取代的二甲基 - (3-芳基丁基)胺化合物的方法
- Patent Title: Process for preparing a substituted dimethyl-(3-arylbutyl)amine compound by homogeneous catalysis
- Patent Title (中): 通过均相催化制备取代的二甲基 - (3-芳基丁基)胺化合物的方法
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Application No.: US12113582Application Date: 2008-05-01
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Publication No.: US08791300B2Publication Date: 2014-07-29
- Inventor: Wolfgang Hell , Markus Kegel , Helmut Buschmann , Felix Spindler , Detlef Heller , Hans-Joachin Drexler
- Applicant: Wolfgang Hell , Markus Kegel , Helmut Buschmann , Felix Spindler , Detlef Heller , Hans-Joachin Drexler
- Applicant Address: DE Aachen
- Assignee: Gruenenthal GmbH
- Current Assignee: Gruenenthal GmbH
- Current Assignee Address: DE Aachen
- Agency: Hunton & Williams LLP
- Priority: DE102005052588 20051102
- Main IPC: C07C211/00
- IPC: C07C211/00

Abstract:
Compounds of the formula II can be hydrogenated to the corresponding butane derivatives in the presence of homogeneous cataslysts composed of metal salts or complexes containing metals selected from the group consisting of Rh, Ir, and Ru and preferably containing diphosphine ligands, with, in addition, excellent optical yields being achieved when one of R2 and R3 is not a hydrogen atom and the diphosphine ligand is chiral.
Public/Granted literature
- US20090043132A1 Process for Preparing a Substituted Dimethyl-(3-arylbutyl)amine Compound by Homogeneous Catalysis Public/Granted day:2009-02-12
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