A securing device for a portable electronic device includes a body and a case is mounted to the body. First and second engaging members are respectively connected to two sides of the body. First and second locking members are respectively and movably connected to the two sides of the body and located corresponding to the first and second engaging members. The first locking member includes a first stop and a first recess, and the second locking member includes a second stop and a second recess. The first/second engaging member is stopped by the first/second stop and is movable in the first/second recess to unlock the secured status. A connection member is pivotably connected to the first and second locking members and is movable by operation of the control member to shift the first and second locking members to allow the first and second engaging members to unlock.