发明授权
US08802396B2 Activated collagen scaffold materials and their special fused active restoration factors
有权
活化胶原蛋白支架材料及其特殊的融合活性修复因子
- 专利标题： Activated collagen scaffold materials and their special fused active restoration factors
- 专利标题（中）： 活化胶原蛋白支架材料及其特殊的融合活性修复因子
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申请号： US12159369申请日： 2006-12-01
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公开(公告)号： US08802396B2公开(公告)日： 2014-08-12
- 发明人: Jianwu Dai , Bing Chen , Hang Lin , Wenjie Sun , Wenxue Zhao
- 申请人： Jianwu Dai , Bing Chen , Hang Lin , Wenjie Sun , Wenxue Zhao
- 申请人地址： CN CN
- 专利权人： Yantai Zhenghai Bio-Technology Co., Ltd.,Institute of Genetics and Developmental Biology Chinese Academy of Science
- 当前专利权人： Yantai Zhenghai Bio-Technology Co., Ltd.,Institute of Genetics and Developmental Biology Chinese Academy of Science
- 当前专利权人地址： CN CN
- 代理机构： Knobbe Martens Olson & Bear LLP
- 优先权： CN200510132792 20051226; CN200610081506 20060524
- 国际申请： PCT/CN2006/003244 WO 20061201
- 国际公布： WO2007/073661 WO 20070705
- 主分类号： C12P21/04
- IPC分类号： C12P21/04 ; A61K51/00
摘要：
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (CBD) at N-/C-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in SEQ ID NO:1 at N-terminus.
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