发明授权
- 专利标题： Arylamino N-heteraryl compounds as MEK inhibitors
- 专利标题（中）： 芳基氨基N-杂芳基化合物作为MEK抑制剂
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申请号： US12815071申请日： 2010-06-14
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公开(公告)号： US08802703B2公开(公告)日： 2014-08-12
- 发明人: Andreas Goutopoulos , Benny C. Askew, Jr. , Nhut Kiet Diep , Srinivasa R. Karra , Matthias Schwarz , Henry Yu
- 申请人： Andreas Goutopoulos , Benny C. Askew, Jr. , Nhut Kiet Diep , Srinivasa R. Karra , Matthias Schwarz , Henry Yu
- 申请人地址： CH Coinsins, Vaud
- 专利权人： Merck Serono S.A.
- 当前专利权人： Merck Serono S.A.
- 当前专利权人地址： CH Coinsins, Vaud
- 代理机构： EMD Serono Research & Development Institute
- 代理商 Thomas W. Brown
- 主分类号： A61K31/465
- IPC分类号： A61K31/465 ; A61K31/4412 ; A61K31/44 ; C07D213/81 ; C07D213/80 ; C07D213/82 ; C07D405/12 ; C07D213/84 ; C07D237/24 ; C07D213/79 ; A61P35/00 ; A61P29/00
摘要：
The invention provides novel arylamino N-heteroaryl MEK inhibitors of Formula (I): Such compounds are MEK inhibitors that are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation. Also disclosed is the treatment of a hyperproliferative disease in mammals, and pharmaceutical compositions containing such compounds.
公开/授权文献
- US20100256149A1 NOVEL ARYLAMINO N-HETERARYL COMPOUNDS AS MEK INHIBITORS 公开/授权日：2010-10-07
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