A method of detecting address spoofing includes receiving an ARP packet at a network device. The ARP packet includes a first address associated with a first network layer and a second address associated with a second network layer. The method also includes accessing a first memory searchable by the first address to obtain a memory reference and retrieving a third address associated with the second network layer from a second memory using the memory reference. The method further includes comparing the second address with the third address and detecting address spoofing if a match is not present between the second address and the third address.