发明授权
US08815863B2 Compounds and therapeutic use thereof for protein kinase inhibition
有权
用于蛋白激酶抑制的化合物及其治疗用途
- 专利标题： Compounds and therapeutic use thereof for protein kinase inhibition
- 专利标题（中）： 用于蛋白激酶抑制的化合物及其治疗用途
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申请号： US13496494申请日： 2010-09-17
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公开(公告)号： US08815863B2公开(公告)日： 2014-08-26
- 发明人: Zhanggui Wu
- 申请人： Zhanggui Wu
- 代理机构： Pinsent Masons LLP
- 代理商 Kening Li
- 国际申请： PCT/US2010/049199 WO 20100917
- 国际公布： WO2011/035077 WO 20110324
- 主分类号： A01N43/58
- IPC分类号： A01N43/58 ; A61K31/50 ; C07D237/26 ; C07D495/02
摘要：
Novel compound having the following formula: (I) wherein Y is N, O, or S. Also disclosed are a pharmaceutical compositions comprising the same, methods for treating cancer using the same, and methods for the synthesis of the same. The novel compounds of the present invention are found to inhibit protein kinases, especially Checkpoint kinase Chk1/Chk2.
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