发明授权
- 专利标题： Heterocyclic amides as rock inhibitors
- 专利标题（中）： 杂环酰胺作为岩石抑制剂
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申请号： US13582195申请日： 2011-03-04
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公开(公告)号： US08815873B2公开(公告)日： 2014-08-26
- 发明人: Dirk Leysen , Olivier Defert , Nadzeya Kaval , Petra Blom , Sandro Boland
- 申请人： Dirk Leysen , Olivier Defert , Nadzeya Kaval , Petra Blom , Sandro Boland
- 申请人地址： BE Diepenbeek
- 专利权人： Amakem NV
- 当前专利权人： Amakem NV
- 当前专利权人地址： BE Diepenbeek
- 代理机构： Dinsmore & Shohl LLP
- 优先权： GB1003395.9 20100302; GB1018996.7 20101110
- 国际申请： PCT/EP2011/053343 WO 20110304
- 国际公布： WO2011/107608 WO 20110909
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D471/22 ; C07D487/04 ; A01N43/42 ; A61K31/44 ; A01N43/38 ; A61K31/40 ; A01N43/06 ; A61K31/38 ; A01N43/02 ; A61K31/335
摘要：
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease.In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and Respiratory diseases.
公开/授权文献
- US20120322801A1 HETEROCYCLIC AMIDES AS ROCK INHIBITORS 公开/授权日：2012-12-20
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