发明授权
- 专利标题: Pyrazole aminopyrimidine derivatives as LRRK2 modulators
- 专利标题(中): 吡唑氨基嘧啶衍生物作为LRRK2调节剂
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申请号: US13292668申请日: 2011-11-09
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公开(公告)号: US08815882B2公开(公告)日: 2014-08-26
- 发明人: Charles Baker-Glenn , Daniel Jon Burdick , Mark Chambers , Bryan K. Chan , Huifen Chen , Anthony Estrada , Zachary Kevin Sweeney
- 申请人: Charles Baker-Glenn , Daniel Jon Burdick , Mark Chambers , Bryan K. Chan , Huifen Chen , Anthony Estrada , Zachary Kevin Sweeney
- 申请人地址: US CA South San Francisco
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理商 Robert C. Hall
- 主分类号: A01N43/54
- IPC分类号: A01N43/54 ; A61K31/505
摘要:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.
公开/授权文献
- US20120157427A1 PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS 公开/授权日:2012-06-21