Techniques are described for managing distributed execution of programs. In some situations, the techniques include determining configuration information to be used for executing a particular program in a distributed manner on multiple computing nodes and/or include providing information and associated controls to a user regarding ongoing distributed execution of one or more programs to enable the user to modify the ongoing distributed execution in various manners. Determined configuration information may include, for example, configuration parameters such as a quantity of computing nodes and/or other measures of computing resources to be used for the executing, and may be determined in various manners, including by interactively gathering values for at least some types of configuration information from an associated user (e.g., via a GUI that is displayed to the user) and/or by automatically determining values for at least some types of configuration information (e.g., for use as recommendations to a user).