发明授权
- 专利标题: Procoagulant peptides
- 专利标题(中): 促凝剂肽
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申请号: US13238751申请日: 2011-09-21
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公开(公告)号: US08822638B2公开(公告)日: 2014-09-02
- 发明人: Friedrich Scheiflinger , Michael Dockal
- 申请人: Friedrich Scheiflinger , Michael Dockal
- 申请人地址: US IL Deerfield CH Glattpark (Opfikon)
- 专利权人: Baxter International Inc.,Baxter Healthcare SA
- 当前专利权人: Baxter International Inc.,Baxter Healthcare SA
- 当前专利权人地址: US IL Deerfield CH Glattpark (Opfikon)
- 代理机构: Marshall, Gerstein & Borun LLP
- 主分类号: C07K7/00
- IPC分类号: C07K7/00
摘要:
A peptide or peptide derivative comprising: (i) WDLYFEIVW;(SEQ ID NO: 1) or (ii) a variant amino acid sequence comprising one, two, three or four L-amino acid substitutions in WDLYFEIVW (SEQ ID NO: 1); or (iii) the retro-inverso variant of the peptide or peptide derivative of either one of parts (i) and (ii), wherein said peptide or peptide derivative has procoagulant activity. A peptide or peptide derivative comprising: (i) an amino acid sequence comprising imfwydcye; or (ii) a variant amino acid sequence comprising one, two, three, four, five or six amino acid substitutions in imfwydcye, wherein said peptide or peptide derivative has procoagulant activity.
公开/授权文献
- US20120077749A1 Biologically Active Peptides 公开/授权日:2012-03-29
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