A color calibration method and an image processing device using the same are provided. The method includes: obtaining a first image of a calibration card having color blocks, each of which corresponds to a standard value; obtaining first sensing values according to the first image, wherein each of the first sensing values corresponds to one of the standard values; generating a calibration table according to the first sensing values and the standard values; determining if a recursive condition is satisfied. The method also includes: obtaining a second image of the calibration card if the recursive condition is not satisfied; obtaining second sensing values according to the second image; adjusting the second sensing values according to the calibration table to generate third sensing values; updating the calibration table according to the third sensing values and the standard values until the recursive condition is satisfied. Accordingly, the calibration table is generated automatically.