发明授权
US08828382B2 Heparin-binding epidermal growth factor-like growth factor binding proteins
有权
肝素结合表皮生长因子样生长因子结合蛋白
- 专利标题: Heparin-binding epidermal growth factor-like growth factor binding proteins
- 专利标题(中): 肝素结合表皮生长因子样生长因子结合蛋白
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申请号: US12680191申请日: 2008-09-26
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公开(公告)号: US08828382B2公开(公告)日: 2014-09-09
- 发明人: Mike Rothe , Norbert Prenzel , Eric Borges , Thore Hettmann , Esther Zwick-Wallasch , Orit Foord
- 申请人: Mike Rothe , Norbert Prenzel , Eric Borges , Thore Hettmann , Esther Zwick-Wallasch , Orit Foord
- 申请人地址: DE Martinsried US CA Thousand Oaks
- 专利权人: U3 Pharma GmbH,Amgen Inc.
- 当前专利权人: U3 Pharma GmbH,Amgen Inc.
- 当前专利权人地址: DE Martinsried US CA Thousand Oaks
- 代理机构: Chao, Hadidi, Stark & Barker LLP
- 代理商 Birgit Millaüer, Esq
- 优先权: EP07018946 20070926
- 国际申请: PCT/EP2008/008233 WO 20080926
- 国际公布: WO2009/040134 WO 20090402
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/22 ; C12P21/08 ; C07H21/04
摘要:
Provided herein are antigen binding proteins, e.g., human and/or monoclonal antibodies that have affinity for heparin-binding epidermal growth factor-like growth factor (HB-EGF) and neutralize the biological functions of this growth factor.
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