发明授权
US08828397B2 Anti-PSGL-1 antibodies and methods of inducing cell death of an activated T cell
有权
抗PSGL-1抗体和诱导活化的T细胞的细胞死亡的方法
- 专利标题: Anti-PSGL-1 antibodies and methods of inducing cell death of an activated T cell
- 专利标题(中): 抗PSGL-1抗体和诱导活化的T细胞的细胞死亡的方法
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申请号: US13616801申请日: 2012-09-14
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公开(公告)号: US08828397B2公开(公告)日: 2014-09-09
- 发明人: Rong-Hwa Lin , Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang
- 申请人: Rong-Hwa Lin , Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang
- 申请人地址: NL Alkmaar
- 专利权人: AbGenomics Cooperatief U.A.
- 当前专利权人: AbGenomics Cooperatief U.A.
- 当前专利权人地址: NL Alkmaar
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/28 ; C07K16/46
摘要:
Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.
公开/授权文献
- US20130101587A1 ANTI-PSGL-1 ANTIBODIES 公开/授权日:2013-04-25
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