发明授权
- 专利标题： Pharmaceutical solid dispersions
- 专利标题（中）： 药物固体分散体
-
申请号： US13610350申请日： 2012-09-11
-
公开(公告)号： US08828442B2公开(公告)日： 2014-09-09
- 发明人: Walter C. Babcock , Dwayne T. Friesen , James A. S. Nightingale , Ravi M. Shanker
- 申请人： Walter C. Babcock , Dwayne T. Friesen , James A. S. Nightingale , Ravi M. Shanker
- 申请人地址： US OR Bend
- 专利权人： Bend Research, Inc.
- 当前专利权人： Bend Research, Inc.
- 当前专利权人地址： US OR Bend
- 代理机构： Klarquist Sparkman, LLP
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K9/16 ; A61K9/14
摘要：
A composition comprises a solid dispersion comprising a low-solubility drug and at least one polymer. In another aspect of the invention, a composition comprises a solid dispersion comprising a low-solubility drug and a stabilizing polymer. At least a major portion of the drug in the dispersion is amorphous. The composition also includes a concentration-enhancing polymer that increases the concentration of the drug in a use environment. The stabilizing polymer has a glass transition temperature that is greater than the glass transition temperature of the concentration-enhancing polymer at a relative humidity of 50%.
公开/授权文献
- US20130029965A1 PHARMACEUTICAL SOLID DISPERSIONS 公开/授权日：2013-01-31
信息查询
