发明授权
- 专利标题： PIM kinase inhibitors and methods of their use
- 专利标题（中）： PIM激酶抑制剂及其使用方法
-
申请号： US13447988申请日： 2012-04-16
-
公开(公告)号： US08829193B2公开(公告)日： 2014-09-09
- 发明人: Matthew Burger , Jiong Lan , Mika Lindvall , Gisele Nishiguchi , Michelle Tetalman
- 申请人： Matthew Burger , Jiong Lan , Mika Lindvall , Gisele Nishiguchi , Michelle Tetalman
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理商 Stephen Johnson
- 主分类号： C07D417/14
- IPC分类号： C07D417/14 ; A61K31/4545 ; A61K31/4439 ; C07D417/12
摘要：
The present invention relates to new compounds of Formulas I and II, their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pim kinase activity and/or the prophylaxis or treatment of cancer.
公开/授权文献
- US20120202851A1 PIM KINASE INHIBITORS AND METHODS OF THEIR USE 公开/授权日：2012-08-09
信息查询
