An information handling system includes a processor that executes multiple instructions or instruction threads within a software application program. The information handling system includes operating system software that manages processor system hardware and software in a multi-tasking environment. In one embodiment, the operating system manages instruction completion stall analysis software to determine the cause or causes of instruction stalls. In another embodiment, the stall analysis software cooperates with the operating system software to store instruction completion stall event data on a per instruction basis while the application program executes. The operating system software may cooperate with the stall analysis software to store instruction completion stall data in memory for later manipulation by system users or other software.