Invention Grant
- Patent Title: Oligo-guluronate and galacturonate compositions
- Patent Title (中): 寡糖醛酸糖苷和半乳糖醛酸组合物
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Application No.: US12595818Application Date: 2008-04-11
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Publication No.: US08841279B2Publication Date: 2014-09-23
- Inventor: Catherine Taylor , Kurt Ingar Draget , Olav Asmund Smidsrod
- Applicant: Catherine Taylor , Kurt Ingar Draget , Olav Asmund Smidsrod
- Applicant Address: NO Trondheim
- Assignee: Norwegian University of Science and Technology
- Current Assignee: Norwegian University of Science and Technology
- Current Assignee Address: NO Trondheim
- Agency: Knobbe Martens Olson & Bear, LLP
- Priority: GB0707096.4 20070412
- International Application: PCT/GB2008/001287 WO 20080411
- International Announcement: WO2008/125828 WO 20081023
- Main IPC: A61K31/715
- IPC: A61K31/715 ; A61K31/70 ; A61K45/06
Abstract:
The invention provides a pharmaceutical composition comprising a macromolecular drug and an oligoguluronate or oligogalacturonate, e.g., having a number average degree of polymerization in the range 5 to 18, a guluronate (or galacturonate) fraction (FG) of at least 0.80, a mannuronate fraction (FM) of no more than 0.20, and having at least 95% mole with a degree of polymerization less than 20. The composition may be used in a method of treatment which comprises administering the composition to a mucosal surface in a human or non-human vertebrate subject.
Public/Granted literature
- US20100152122A1 OLIGO-GULURONATE AND GALACTURONATE COMPOSITIONS Public/Granted day:2010-06-17
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