发明授权
US08841286B2 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
有权
用于治疗和预防肺细菌感染的可吸入的氨曲南溶解物制剂
- 专利标题： Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
- 专利标题（中）： 用于治疗和预防肺细菌感染的可吸入的氨曲南溶解物制剂
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申请号： US13245705申请日： 2011-09-26
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公开(公告)号： US08841286B2公开(公告)日： 2014-09-23
- 发明人: Alan Bruce Montgomery
- 申请人： Alan Bruce Montgomery
- 申请人地址： US CA Foster City
- 专利权人： Gilead Sciences, Inc.
- 当前专利权人： Gilead Sciences, Inc.
- 当前专利权人地址： US CA Foster City
- 代理机构： Gilead Sciences, Inc.
- 代理商 Steven R. Eck
- 主分类号： A61K31/397
- IPC分类号： A61K31/397 ; A61K9/12 ; A61K9/00 ; A61K31/427
摘要：
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam lysinate delivered as an aerosol or dry powder formulation.
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