发明授权
- 专利标题: Antimicrobials
- 专利标题(中): 抗生素
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申请号: US13130440申请日: 2009-11-18
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公开(公告)号: US08841306B2公开(公告)日: 2014-09-23
- 发明人: Rajesh Jain , Sanjay Trehan , Jagattaran Das , Sandeep Kanwar , Sitaram Kumar Magadi , Sudhir Kumar Sharma
- 申请人: Rajesh Jain , Sanjay Trehan , Jagattaran Das , Sandeep Kanwar , Sitaram Kumar Magadi , Sudhir Kumar Sharma
- 申请人地址: IN New Delhi
- 专利权人: Panacea Biotec Ltd.
- 当前专利权人: Panacea Biotec Ltd.
- 当前专利权人地址: IN New Delhi
- 代理机构: Lowe Hauptman & Ham, LLP
- 优先权: IN2623/DEL/2008 20081120
- 国际申请: PCT/IN2009/000658 WO 20091118
- 国际公布: WO2010/058423 WO 20100527
- 主分类号: A61K31/33
- IPC分类号: A61K31/33 ; C07D413/14 ; C07D417/12 ; C07D487/04 ; C07D413/12 ; C07D263/20
摘要:
The present invention relates to novel phenyl oxazolidinone compounds of formula I, their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of formula I or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of formula I and methods of using them. The compounds of the present invention are useful as antimicrobial agents, effective against a number of aerobic and/or anaerobic Gram positive and/or Gram negative pathogens such as multi drug resistant species of Staphylococcus, Streptococcus, Enterococcus, Bacterioides, Clostridia, H. influenza, Moraxella, acid-fast organisms such as Mycobacterium tuberculosis as well as Linezolid resistant species of Staphylococcus and Enterococcus.
公开/授权文献
- US20110245258A1 NOVEL ANTIMICROBIALS 公开/授权日:2011-10-06
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