Invention Grant
US08841455B2 Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as cFMS inhibitors
有权
取代的N-（1H-吲唑-4-基）咪唑并[1,2-a]吡啶-3-甲酰胺化合物，为cFMS抑制剂
![Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as cFMS inhibitors](/docs/US/2014-09-23/US08841455B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as cFMS inhibitors
- Patent Title (中): 取代的N-（1H-吲唑-4-基）咪唑并[1,2-a]吡啶-3-甲酰胺化合物，为cFMS抑制剂
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Application No.: US13517938Application Date: 2010-12-20
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Publication No.: US08841455B2Publication Date: 2014-09-23
- Inventor: Mark Laurence Boys , Michael F. Bradley , Robert Kirk DeLisle , D. David Hennings , April L. Kennedy , Fredrik P. Marmsater , Matthew David Medina , Mark C. Munson , Bryson Rast , James P. Rizzi , Martha E. Rodriguez , George T. Topalov , Qian Zhao
- Applicant: Mark Laurence Boys , Michael F. Bradley , Robert Kirk DeLisle , D. David Hennings , April L. Kennedy , Fredrik P. Marmsater , Matthew David Medina , Mark C. Munson , Bryson Rast , James P. Rizzi , Martha E. Rodriguez , George T. Topalov , Qian Zhao
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Agent Sarah S. Mastous
- International Application: PCT/US2010/061341 WO 20101220
- International Announcement: WO2011/079076 WO 20110630
- Main IPC: C07D491/02
- IPC: C07D491/02 ; C07D231/56
![Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as cFMS inhibitors](/abs-image/US/2014/09/23/US08841455B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of Formula (I): and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4 and R5 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases and pain.
Public/Granted literature
- US20120258952A1 Substituted N-(1H-Indazol-4-yl)Imidazo[1,2-a]Pyridine-3-Carboxamide Compounds as cFMS Inhibitors Public/Granted day:2012-10-11
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