发明授权
US08846101B2 Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions
有权
薄膜包衣和/或颗粒状含钙化合物及其在药物组合物中的用途
- 专利标题： Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions
- 专利标题（中）： 薄膜包衣和/或颗粒状含钙化合物及其在药物组合物中的用途
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申请号： US12085799申请日： 2006-12-07
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公开(公告)号： US08846101B2公开(公告)日： 2014-09-30
- 发明人: Jan Y. Piene
- 申请人： Jan Y. Piene
- 申请人地址： NO Asker
- 专利权人： Takeda Nycomed AS
- 当前专利权人： Takeda Nycomed AS
- 当前专利权人地址： NO Asker
- 代理机构： Choate, Hall & Stewart LLP
- 代理商 Charles E. Lyon
- 优先权： DK200501736 20051207; DK200601203 20060915
- 国际申请： PCT/DK2006/000696 WO 20061207
- 国际公布： WO2007/065441 WO 20070614
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; B23B29/00 ; B32B9/04 ; B32B9/00 ; B05D7/00 ; A61P43/00
摘要：
Calcium-containing compounds have been at least partly film-coated and/or granulated with a water-soluble substance and a water-soluble polymeric substance and use of such coated compounds in pharmaceutical compositions. The at least partly film-coated and/or granulated calcium-containing compounds have proved suitable for the preparation of tablets having a very high load of elemental calcium and a conveniently small size. A drug load of about 96% or more is obtained in tablets of the invention that have sufficient mechanical and organoleptic properties.
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