Anti-theft lockset is disclosed. Lock column and frame body are arranged in lock core. Outer side of lock column is matched with a long slot on the inner wall of lock shell. Inner side of lock column is provided with a crown pillar, and lock core is provided with a sliding chute for causing lock column to slide and a first through hole for causing frame body to move. Crown pillar is contacted with a first lock ball. Lock core is internally provided with lock ball holes matched with first and second lock balls. One end of the second lock ball is contacted with the frame body. The lock core is provided with a containing slot for causing the first lock ball and a locking plate to move up and down. The containing slot is communicated with a key hole. The locking plate is provided with a second through hole.