The present invention relates to a device for internal fixation of the bone fragments (2, 3) in a radius fracture (4). The device comprises at least one body (1) for abutment against the bone fragments (2, 3) in the radius fracture (4), and fixing elements (6, 7) which are intended to be locked to the body for fixation of said bone fragments. The body (1) itself has in a distal end portion (1a) at least two predrilled holes (8) for fixing elements (6), and in a proximal end portion (1b) at least two predrilled holes (9) for fixing elements (7). To allow effective optimum internal fixation of the bone fragments in the radius fracture, the predrilled holes (8, 9) run obliquely relative to a longitudinal axis (L) of the body (1) so that all of the fixing elements (6, 7) which, after the body has been caused to abut against the bone fragments (2, 3) in the radius fracture (4), are introduced into said bone fragments through holes (8, 9) in the body's distal end portion (1a) and proximal end portion (1b) cross the radius fracture (4) as viewed in the transverse direction of the body. Each fixing element (6, 7) has at least one fixing portion (10; 10a, 10b) for locking the fixing element in the bone fragments (2, 3) in the radius fracture (4) and for locking the fixing element to the body (1).