Invention Grant
- Patent Title: Radiolabelled PDE10 ligands
- Patent Title (中): 放射性标记的PDE10配体
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Application No.: US13505157Application Date: 2010-10-27
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Publication No.: US08852554B2Publication Date: 2014-10-07
- Inventor: José Ignacio Andrés-Gil , Meri De Angelis , Guy Maurits R. Bormans , Sofie Jeanne Leopoldine Celen
- Applicant: José Ignacio Andrés-Gil , Meri De Angelis , Guy Maurits R. Bormans , Sofie Jeanne Leopoldine Celen
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Hal B. Woodrow
- Priority: EP09174702 20091030
- International Application: PCT/EP2010/066237 WO 20101027
- International Announcement: WO2011/051324 WO 20110505
- Main IPC: A61K51/04
- IPC: A61K51/04 ; C07D401/14
Abstract:
The present invention relates to novel, selective, radiolabelled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo.
Public/Granted literature
- US20120213703A1 RADIOLABELLED PDE10 LIGANDS Public/Granted day:2012-08-23
Information query
