Invention Grant
- Patent Title: Animal model for evaluating vasomotor response in vivo
- Patent Title (中): 用于评估体内血管舒缩反应的动物模型
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Application No.: US12603360Application Date: 2009-10-21
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Publication No.: US08852556B2Publication Date: 2014-10-07
- Inventor: Tom Jay Parry , Bruce P. Damiano , Edward C. Giardino , Margery A. Connelly
- Applicant: Tom Jay Parry , Bruce P. Damiano , Edward C. Giardino , Margery A. Connelly
- Applicant Address: US NJ Raritan
- Assignee: Janssen Research & Development LLC
- Current Assignee: Janssen Research & Development LLC
- Current Assignee Address: US NJ Raritan
- Agency: Johnson & Johnson
- Agent Bernard F. Plantz
- Main IPC: A61K49/00
- IPC: A61K49/00
Abstract:
A method for evaluating the effect of a compound on vasomotor response in vivo comprises the steps of administering said compound to a rabbit and measuring the diameter of the vessel lumen of a central ear artery of said rabbit in comparison with the baseline diameter of the vessel lumen of said central ear artery of said rabbit, said baseline diameter being measured prior to the administration of said compound.
Public/Granted literature
- US20100189654A1 ANIMAL MODEL FOR EVALUATING VASOMOTOR RESPONSE IN VIVO Public/Granted day:2010-07-29
Information query
