Invention Grant
- Patent Title: Compositions and methods for treating and preventing skeletal muscle deficiencies
- Patent Title (中): 用于治疗和预防骨骼肌缺乏的组合物和方法
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Application No.: US12747073Application Date: 2008-12-17
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Publication No.: US08852568B2Publication Date: 2014-10-07
- Inventor: Rainer Ng , Joseph M. Metzger , Lorraine Reeve , Bruce Markham
- Applicant: Rainer Ng , Joseph M. Metzger , Lorraine Reeve , Bruce Markham
- Applicant Address: US MI Ann Arbor US MI Ann Arbor
- Assignee: The Regents of the University of Michigan,Phrixus Pharmaceuticals, Inc.
- Current Assignee: The Regents of the University of Michigan,Phrixus Pharmaceuticals, Inc.
- Current Assignee Address: US MI Ann Arbor US MI Ann Arbor
- Agency: Casimir Jones SC
- International Application: PCT/US2008/087185 WO 20081217
- International Announcement: WO2009/079562 WO 20090625
- Main IPC: A61K31/77
- IPC: A61K31/77 ; A61K31/765
Abstract:
The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca2+ imbalance; skeletal muscle having microtears).
Public/Granted literature
- US20110033412A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES Public/Granted day:2011-02-10
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