Invention Grant
- Patent Title: Cardiac muscle repair or regeneration using bone marrow-derived stem cells
- Patent Title (中): 使用骨髓干细胞进行心肌修复或再生
-
Application No.: US13370065Application Date: 2012-02-09
-
Publication No.: US08852574B2Publication Date: 2014-10-07
- Inventor: Mark F. Pittenger , Stephen L. Gordon , Alastair Morgan Mackay
- Applicant: Mark F. Pittenger , Stephen L. Gordon , Alastair Morgan Mackay
- Applicant Address: CH
- Assignee: Mesoblast International Sarl
- Current Assignee: Mesoblast International Sarl
- Current Assignee Address: CH
- Agency: McAndrews, Held & Malloy, Ltd.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/85
Abstract:
Disclosed are compositions and methods for repairing and/or regenerating cardiac tissue by administering adult bone marrow-derived stem cells to an individual. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.
Public/Granted literature
- US20120148545A1 CARDIAC MUSCLE REPAIR OR REGENERATION USING BONE MARROW-DERIVED STEM CELLS Public/Granted day:2012-06-14
Information query
