Invention Grant
US08852609B2 Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same
有权
基孔肯雅病毒蛋白质的共有序列，编码它们的核酸分子，以及使用它们的组合物和方法
- Patent Title: Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same
- Patent Title (中): 基孔肯雅病毒蛋白质的共有序列，编码它们的核酸分子，以及使用它们的组合物和方法
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Application No.: US12936186Application Date: 2009-04-06
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Publication No.: US08852609B2Publication Date: 2014-10-07
- Inventor: David B. Weiner , Karuppiah Muthumani
- Applicant: David B. Weiner , Karuppiah Muthumani
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Pepper Hamilton LLP
- International Application: PCT/US2009/039656 WO 20090406
- International Announcement: WO2009/124312 WO 20091008
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C07H21/04 ; C07K14/005 ; C12N7/00 ; A61K39/00 ; A61K39/39
Abstract:
Consensus CHIKV E1 protein, consensus CHIKV E2 protein, consensus CHIKV capsid protein, or fragments and homologues thereof, and nucleic acid molecules that encode the same are disclosed. A consensus CHIKV Env protein which includes CHIKV E1 consensus protein, CHIKV E2 consensus protein, CHIKV E3 consensus protein, or fragments and homologues thereof and nucleic acid molecules that encode the same are also disclosed. Compositions and recombinant vaccines comprising CHIKV consensus proteins, and methods of using them are disclosed.
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