Invention Grant
- Patent Title: Chimeric small molecules for the recruitment of antibodies to cancer cells
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Application No.: US13173480Application Date: 2011-06-30
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Publication No.: US08852630B2Publication Date: 2014-10-07
- Inventor: David Spiegel , Ryan Murelli , Andrew Zhang
- Applicant: David Spiegel , Ryan Murelli , Andrew Zhang
- Applicant Address: US CT New Haven
- Assignee: Yale University
- Current Assignee: Yale University
- Current Assignee Address: US CT New Haven
- Agent Henry D. Coleman; R. Neil Sudol
- Main IPC: A61K9/127
- IPC: A61K9/127
Abstract:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
Public/Granted literature
- US20120034295A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS Public/Granted day:2012-02-09
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