Invention Grant
US08852880B2 Test for predicting neutralization of asparaginase activity 有权
测试预测天冬酰胺酶活性的中和

  • Patent Title: Test for predicting neutralization of asparaginase activity
  • Patent Title (中): 测试预测天冬酰胺酶活性的中和
  • Application No.: US13127756
    Application Date: 2009-11-06
  • Publication No.: US08852880B2
    Publication Date: 2014-10-07
  • Inventor: Yann Godfrin
  • Applicant: Yann Godfrin
  • Applicant Address: FR Lyons
  • Assignee: Erytech Pharma
  • Current Assignee: Erytech Pharma
  • Current Assignee Address: FR Lyons
  • Agency: Stites & Harbison, PLLC.
  • Agent Stephen J. Weyer, Esq.
  • Priority: FR0857604 20081107
  • International Application: PCT/EP2009/064793 WO 20091106
  • International Announcement: WO2010/052315 WO 20100514
  • Main IPC: C12Q1/44
  • IPC: C12Q1/44 C12Q1/00 C12Q1/34
Test for predicting neutralization of asparaginase activity
Abstract:
Method of in vitro measurement of the presence of factors that are able to neutralize asparaginase activity in a sample of blood, plasma, serum or derived medium that may contain asparaginase neutralizing factors, obtained from a patient, comprising mixing of said sample with asparaginase, incubation of said mixture, then measurement of the residual asparaginase activity in the mixture and determination or quantification of the presence of said neutralizing factors. Method for predicting the efficacy of a treatment with asparaginase.
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