Invention Grant
US08852902B2 Producing a trimethylpentanoic acid using hybrid polyketide synthases
有权
使用混合聚酮化合物合酶生产三甲基戊酸
- Patent Title: Producing a trimethylpentanoic acid using hybrid polyketide synthases
- Patent Title (中): 使用混合聚酮化合物合酶生产三甲基戊酸
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Application No.: US13302966Application Date: 2011-11-22
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Publication No.: US08852902B2Publication Date: 2014-10-07
- Inventor: Leonard Katz , Jeffrey L. Fortman , Jay D. Keasling
- Applicant: Leonard Katz , Jeffrey L. Fortman , Jay D. Keasling
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C12N15/52
- IPC: C12N15/52 ; C12P7/40
Abstract:
The present invention provides for a polyketide synthase (PKS) capable of synthesizing trimethylpentanoic acid. The present invention also provides for a host cell comprising the PKS and when cultured produces the trimethylpentanoic acid. The present invention also provides for a method of producing the trimethylpentanoic acid, comprising: providing a host cell of the present invention, and culturing said host cell in a suitable culture medium such that the trimethylpentanoic acid is produced, optionally isolating the trimethylpentanoic acid, and optionally, reducing the isolated trimethylpentanoic acid into a trimethylpentanol or an iso-octane.
Public/Granted literature
- US20120219998A1 Producing a Trimethylpentanoic Acid Using Hybrid Polyketide Synthases Public/Granted day:2012-08-30
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