Invention Grant
US08852939B2 Use of Vgll3 activity modulator for the modulation of adipogenesis
有权
使用Vgll3活性调节剂调节脂肪形成
- Patent Title: Use of Vgll3 activity modulator for the modulation of adipogenesis
- Patent Title (中): 使用Vgll3活性调节剂调节脂肪形成
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Application No.: US13201011Application Date: 2010-02-16
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Publication No.: US08852939B2Publication Date: 2014-10-07
- Inventor: Diana Hall , Maria Jimenez , Carine Poussin , Bernard Thorens
- Applicant: Diana Hall , Maria Jimenez , Carine Poussin , Bernard Thorens
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Lathrop & Gage LLP
- Agent James H. Velema, Esq.
- Priority: EP09290115 20090218
- International Application: PCT/IB2010/050692 WO 20100216
- International Announcement: WO2010/095096 WO 20100826
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A01N63/00 ; C12N5/02 ; C12P21/04 ; C07K14/46 ; G01N33/68 ; G01N33/53
Abstract:
The present invention concerns Vgll3 a new target involved in adipogenesis modulation. Further, the present invention relates to methods to increase Vgll3 activity in adipocytes and preadipocytes. In addition, pharmaceutical composition comprising Vgll3 activity enhancing molecules in order to enhance the Vgll3 activity in a target tissue are also provided. These methods, compositions and molecules can be useful to modulate adipogenesis and thus treat obesity and related disorders.
Public/Granted literature
- US20120101150A1 USE OF VGII3 ACTIVITY MODULATOR FOR THE MODULATION OF ADIPOGENESIS Public/Granted day:2012-04-26
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