Invention Grant
- Patent Title: Method for producing induced pluripotent stem cells
- Patent Title (中): 诱导多能干细胞的制备方法
-
Application No.: US13579314Application Date: 2011-02-18
-
Publication No.: US08852941B2Publication Date: 2014-10-07
- Inventor: Masaki Mori , Hideshi Ishii , Norikatsu Miyoshi , Yuichiro Doki , Masahiro Tanemura , Kenichi Nagai , Hiromitsu Hoshino , Yoshiaki Omura , Naotsugu Haraguchi , Susumu Miyazaki
- Applicant: Masaki Mori , Hideshi Ishii , Norikatsu Miyoshi , Yuichiro Doki , Masahiro Tanemura , Kenichi Nagai , Hiromitsu Hoshino , Yoshiaki Omura , Naotsugu Haraguchi , Susumu Miyazaki
- Applicant Address: JP Osaka
- Assignee: Osaka University
- Current Assignee: Osaka University
- Current Assignee Address: JP Osaka
- Agency: Casimir Jones S.C.
- Priority: JP2010-034008 20100218
- International Application: PCT/JP2011/053457 WO 20110218
- International Announcement: WO2011/102444 WO 20110825
- Main IPC: C12N5/07
- IPC: C12N5/07 ; C12N15/00 ; G01N33/50 ; C12N5/074
Abstract:
A major object of the present invention is to provide a method for producing induced pluripotent stem cells with low tumorigenesis potential and high induction efficiency.The invention provides a method for producing induced pluripotent stem cells comprising the step of introducing one or more nucleic acids that facilitate expression of at least one gene selected from the group consisting of NANOG, SOX2, OCT3/4, KLF4, LIN28, and c-MYC into somatic cells.
Public/Granted literature
- US20130065243A1 METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS Public/Granted day:2013-03-14
Information query
