Invention Grant
US08853145B2 BLID; a novel protein domain for interaction with the Bcl-2 family of proteins
有权
BLID; 用于与Bcl-2蛋白家族相互作用的新型蛋白质结构域
- Patent Title: BLID; a novel protein domain for interaction with the Bcl-2 family of proteins
- Patent Title (中): BLID; 用于与Bcl-2蛋白家族相互作用的新型蛋白质结构域
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Application No.: US13677280Application Date: 2012-11-14
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Publication No.: US08853145B2Publication Date: 2014-10-07
- Inventor: Carlos Witte-Hoffmann
- Applicant: Carlos Witte-Hoffmann
- Main IPC: C07K14/475
- IPC: C07K14/475 ; C12P21/06 ; C07H21/02 ; C07K14/47
Abstract:
In this invention, a novel protein interaction domain is provided along with several of its variants. This domain is involved in protein-protein interactions with the Bcl-2 family of proteins. It is named BLID (Bcl2 family of proteins Like Interaction Domain). Use of BLID and its variants for modulating cellular activity is presented. BLID, its variants and or anti-BLID antibodies could be useful as a screening tool as well as for discovery of drugs that help fight pathological states like degenerative diseases, cerebral or cardiac ischemic hypoxic disorders, cancer and autoimmunity.
Public/Granted literature
- US20130323752A1 BLID; a novel protein domain for interaction with the Bcl-2 family of proteins Public/Granted day:2013-12-05
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