Invention Grant
- Patent Title: Oligopeptide improving differentiation of osteoblasts
- Patent Title (中): 寡肽改善成骨细胞的分化
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Application No.: US13579861Application Date: 2010-02-26
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Publication No.: US08853164B2Publication Date: 2014-10-07
- Inventor: Eun Jung Kang , Tae Gwan Eom , Gyu Ok Choi
- Applicant: Eun Jung Kang , Tae Gwan Eom , Gyu Ok Choi
- Applicant Address: KR Seoul
- Assignee: Osstemimplant Co., Ltd.
- Current Assignee: Osstemimplant Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Seed IP Law Group PLLC
- International Application: PCT/KR2010/001262 WO 20100226
- International Announcement: WO2011/105648 WO 20110109
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/04 ; A61K38/10 ; C07K4/00 ; C07K7/08 ; A61L27/54 ; A61L27/22 ; A61L27/56 ; C07K14/51
Abstract:
The present disclosure relates to oligopeptides applicable to a dental implant, which are selected from the group consisting of PEP7 (SEQ ID NO:1), PEP71 (SEQ ID NO:2), EP72 (SEQ ID NO:3), PEP73 (SEQ ID NO:4), PEP74 (SEQ ID NO:5), PEP75 (SEQ ID NO:6) and PEP76 (SEQ ID NO:7). The oligopeptides have very high reactivity for a BMP-specific receptor to increase osteoblastic differentiation and calcification, thereby showing improved osteointegration and osteogenesis.
Public/Granted literature
- US20120316118A1 OLIGOPEPTIDE IMPROVING DIFFERENTIATION OF OSTEOBLASTS Public/Granted day:2012-12-13
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