发明授权
- 专利标题： Short-chain cationic polyamino acid and use thereof
- 专利标题（中）： 短链阳离子聚氨基酸及其用途
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申请号： US13258663申请日： 2011-02-23
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公开(公告)号： US08853167B2公开(公告)日： 2014-10-07
- 发明人: Yasuki Kato , Atsushi Ishii , Naoya Shibata , Tatsuyuki Hayashi , Kazunori Kataoka , Kanjiro Miyata , Nobuhiro Nishiyama
- 申请人： Yasuki Kato , Atsushi Ishii , Naoya Shibata , Tatsuyuki Hayashi , Kazunori Kataoka , Kanjiro Miyata , Nobuhiro Nishiyama
- 申请人地址： JP Kashiwa-Shi
- 专利权人： NanoCarrier Co., Ltd.
- 当前专利权人： NanoCarrier Co., Ltd.
- 当前专利权人地址： JP Kashiwa-Shi
- 代理机构： J-Tek Law PLLC
- 代理商 Jeffrey D. Tekanic
- 优先权： JP2010-037014 20100223
- 国际申请： PCT/JP2011/053917 WO 20110223
- 国际公布： WO2011/105402 WO 20110901
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; C08G69/10 ; C12N15/11
摘要：
The present invention provides a cationic polyamino acid suitable for a carrier that can form a stable complex with a nucleic acid under a physiological condition and release the nucleic acid in cells suitably. The cationic polyamino acid can associate with a nucleic acid and includes a cationic amino acid residue having a cationic group in a side chain and a hydrophobic amino acid residue having a hydrophobic group in a side chain. The cationic polyamino acid includes 1 to 20 units of the cationic amino acid residue and is represented by the following formula (1). The meaning of each symbol in the formula is as shown in the description.
公开/授权文献
- US20120149649A1 SHORT-CHAIN CATIONIC POLYAMINO ACID AND USE THEREOF 公开/授权日：2012-06-14
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