Invention Grant
- Patent Title: Synthetic glycolipid and use thereof
- Patent Title (中): 合成糖脂及其用途
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Application No.: US13577159Application Date: 2011-02-04
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Publication No.: US08853173B2Publication Date: 2014-10-07
- Inventor: Takuya Tashiro , Kenji Mori , Masao Shiozaki , Masaru Taniguchi , Hiroshi Watarai
- Applicant: Takuya Tashiro , Kenji Mori , Masao Shiozaki , Masaru Taniguchi , Hiroshi Watarai
- Applicant Address: JP Wako
- Assignee: RIKEN
- Current Assignee: RIKEN
- Current Assignee Address: JP Wako
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2010-024859 20100205
- International Application: PCT/JP2011/052415 WO 20110204
- International Announcement: WO2011/096536 WO 20110811
- Main IPC: C07H17/02
- IPC: C07H17/02 ; A61K31/7028 ; A61P31/04 ; A61K31/7032 ; C07H15/04

Abstract:
A compound represented by the following formula (1): wherein R1 is an aldopyranose residue wherein the 6-hydroxyl group is optionally alkylated, R2 is a C1-26 hydrocarbon group optionally having substituent(s), R3 is a hydrogen atom or a C1-26 hydrocarbon group optionally having substituent(s), R4 is a C1-21 hydrocarbon group optionally having substituent(s), X is an oxygen atom or —CH2—, and Y is —CH2—, —CH(OH)— or —CH═CH—, or a salt thereof is useful for the prophylaxis or treatment of cancer or infection, since it can preferentially induce production of IFN-γ of NKT cells.
Public/Granted literature
- US20130005669A1 NOVEL SYNTHETIC GLYCOLIPID AND USE THEREOF Public/Granted day:2013-01-03
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