发明授权
- 专利标题： Antisense modulation of PTP1B expression
- 专利标题（中）： PTP1B表达的反义调制
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申请号： US13177462申请日： 2011-07-06
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公开(公告)号： US08853178B2公开(公告)日： 2014-10-07
- 发明人: Sanjay Bhanot , Lex M. Cowsert , Jacqueline R. Wyatt , Brett P. Monia , Madelline M. Butler , Robert McKay , Susan M. Freier , Kenneth W. Dobie
- 申请人： Sanjay Bhanot , Lex M. Cowsert , Jacqueline R. Wyatt , Brett P. Monia , Madelline M. Butler , Robert McKay , Susan M. Freier , Kenneth W. Dobie
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Isis Pharmaceuticals, Inc Patent Dept. Knobbe Martens
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
公开/授权文献
- US20120077862A1 ANTISENSE MODULATION OF PTP1B EXPRESSION 公开/授权日：2012-03-29
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