Invention Grant
- Patent Title: Prognosis and treatment of breast cancer
- Patent Title (中): 乳腺癌的预后与治疗
-
Application No.: US13954037Application Date: 2013-07-30
-
Publication No.: US08853183B2Publication Date: 2014-10-07
- Inventor: William B. Kinlaw, III
- Applicant: Trustees of Darmouth College
- Applicant Address: US NH Hanover
- Assignee: Trustees of Dartmouth College
- Current Assignee: Trustees of Dartmouth College
- Current Assignee Address: US NH Hanover
- Agency: Licata & Tyrrell P.C.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07K16/18 ; C12Q1/68 ; G01N33/68 ; C12N15/113 ; C07K16/30 ; G01N33/574
Abstract:
The present invention relates to an antibody which specifically binds a Spot 14 (S14 or THRSP) protein in human breast cancer cells and a method for using the same to predict disease-free survival and select treatment modalities for breast cancer. The present invention is also a method for inducing apoptosis in breast cancer cells by inhibiting the expression or activity of Spot 14. Compositions and methods for treating breast cancer are also provided.
Public/Granted literature
- US20130336983A1 PROGNOSIS AND TREATMENT OF BREAST CANCER Public/Granted day:2013-12-19
Information query
IPC分类:
