Invention Grant
- Patent Title: Coferons and methods of making and using them
- Patent Title (中): 咖啡因及其使用方法
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Application No.: US12937053Application Date: 2009-04-09
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Publication No.: US08853185B2Publication Date: 2014-10-07
- Inventor: Francis Barany , Maneesh Pingle , Donald Bergstrom , Sarah Filippa Giardina
- Applicant: Francis Barany , Maneesh Pingle , Donald Bergstrom , Sarah Filippa Giardina
- Applicant Address: US NY Ithaca US IN West Lafayette
- Assignee: Cornell University,Purdue Research Foundation
- Current Assignee: Cornell University,Purdue Research Foundation
- Current Assignee Address: US NY Ithaca US IN West Lafayette
- Agency: LeClairRyan, a Professional Corporation
- International Application: PCT/US2009/002223 WO 20090409
- International Announcement: WO2009/126290 WO 20091015
- Main IPC: A61K31/69
- IPC: A61K31/69 ; C07F5/02 ; C40B30/04 ; C40B50/04

Abstract:
A monomer useful in prepaπng therapeutic compounds includes a diversity element which potentially binds to a target molecule with a dissociation constant of less than 300 11 M and a linker element connected to the diversity element The linker element has a molecular weight less than 500 daltons, is connected, directly or indirectly through a connector, to said diversity element, and is capable of forming a reversible covalent bond or noncovalent interaction with a binding partner of the linker element The monomers can be covalently or non-covalently linked together to form a therapeutic multimer or a precursor thereof.
Public/Granted literature
- US20110263688A1 COFERONS AND METHODS OF MAKING AND USING THEM Public/Granted day:2011-10-27
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