Invention Grant
US08853196B2 Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
有权
氨基荧光素，氨基硫辛烷和氨基-1,2,3,4-四氢喹啉衍生物，含有它们的药物组合物及其在治疗中的用途
- Patent Title: Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
- Patent Title (中): 氨基荧光素，氨基硫辛烷和氨基-1,2,3,4-四氢喹啉衍生物，含有它们的药物组合物及其在治疗中的用途
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Application No.: US13566051Application Date: 2012-08-03
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Publication No.: US08853196B2Publication Date: 2014-10-07
- Inventor: Wilhelm Amberg , Udo Lange , Frauke Pohlki
- Applicant: Wilhelm Amberg , Udo Lange , Frauke Pohlki
- Applicant Address: DE Wiesbaden
- Assignee: AbbVie Deutschland GmbH & Co. KG
- Current Assignee: AbbVie Deutschland GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Main IPC: A61K31/397
- IPC: A61K31/397 ; A61K31/4155 ; A61K31/4178 ; A61K31/381 ; A61K31/352 ; A61K31/35 ; C07D233/54 ; C07D231/10 ; C07D405/02 ; C07D405/14 ; C07D407/02 ; C07D205/04 ; C07D409/02 ; C07D311/04 ; C07D409/12 ; C07D407/12 ; C07D405/12 ; C07D311/58
Abstract:
The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors.
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