发明授权
US08853226B2 Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors
有权
三环化合物作为TNF-α合成的调节剂和PDE4抑制剂
- 专利标题： Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors
- 专利标题（中）： 三环化合物作为TNF-α合成的调节剂和PDE4抑制剂
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申请号： US13040382申请日： 2011-03-04
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公开(公告)号： US08853226B2公开(公告)日： 2014-10-07
- 发明人: Adnan M. M. Mjalli , Bapu Gaddam , Dharma Rao Polisetti , Matthew J. Kostura , Mustafa Guzel
- 申请人： Adnan M. M. Mjalli , Bapu Gaddam , Dharma Rao Polisetti , Matthew J. Kostura , Mustafa Guzel
- 申请人地址： US NC High Point
- 专利权人： High Point Pharmaceuticals, LLC
- 当前专利权人： High Point Pharmaceuticals, LLC
- 当前专利权人地址： US NC High Point
- 代理商 Samuel B. Rollins
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D471/04
摘要：
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to rheumatoid arthritis.
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