Invention Grant
- Patent Title: Inhibitors of JAK
- Patent Title (中): JAK抑制剂
-
Application No.: US13717569Application Date: 2012-12-17
-
Publication No.: US08853230B2Publication Date: 2014-10-07
- Inventor: Shawn M. Bauer , Jack W. Rose , Yonghong Song , Qing Xu , Mukund Mehrotra , Wolin Huang , Anjali Pandey
- Applicant: Portola Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Portola Pharmaceuticals, Inc.
- Current Assignee: Portola Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D403/12 ; C07D417/14 ; C07D403/14 ; C07D401/12 ; C07D213/82 ; C07D417/12 ; C07D239/48
Abstract:
The present invention is directed to compounds of formula I and tautomers and pharmaceutically acceptable salts thereof which are selective inhibitors of JAK. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK activity, and methods to prevent or treat a number of conditions mediated at least in part by JAK activity.
Public/Granted literature
- US20130137673A1 INHIBITORS OF JAK Public/Granted day:2013-05-30
Information query
IPC分类:
