Invention Grant
- Patent Title: Peripheral opioid receptor antagonists and uses thereof
- Patent Title (中): 外周阿片受体拮抗剂及其用途
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Application No.: US14018259Application Date: 2013-09-04
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Publication No.: US08853232B2Publication Date: 2014-10-07
- Inventor: Alfred A. Avey , Appavu Chandrasekaren , Harold D. Doshan , Julio Perez , Yakov Rotshteyn
- Applicant: Progenics Pharmaceuticals, Inc.
- Applicant Address: US NJ Madison US NY Tarrytown
- Assignee: Wyeth LLC,Progenics Pharmaceuticals., Inc.
- Current Assignee: Wyeth LLC,Progenics Pharmaceuticals., Inc.
- Current Assignee Address: US NJ Madison US NY Tarrytown
- Agency: McCarter & English, LLP
- Agent Jonathan M. Sparks; Maneesh Gulati, Esq.
- Main IPC: A61K31/485
- IPC: A61K31/485 ; C07D489/08
Abstract:
The present invention provides a compound of formula I: wherein R1, R2, R2′ and X− are as defined and described herein, methods of manufacture thereof and compositions thereof, useful for example as peripheral mu opioid receptor antagonists in treatment of side effects of opioid administration.
Public/Granted literature
- US20140142132A1 PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF Public/Granted day:2014-05-22
Information query
IPC分类:
