Invention Grant
- Patent Title: Thalidomide analogs
- Patent Title (中): 沙利度胺类似物
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Application No.: US13648625Application Date: 2012-10-10
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Publication No.: US08853253B2Publication Date: 2014-10-07
- Inventor: Nigel H. Greig , Harold Holloway , Arnold Brossi , Xiaoxiang Zhu , Tony Giordano , Qian-sheng Yu , William D. Figg
- Applicant: Nigel H. Greig , Harold Holloway , Tony Giordano , Qian-sheng Yu , William D. Figg
- Applicant Address: US OH Cincinnati
- Assignee: P2D, Inc.
- Current Assignee: P2D, Inc.
- Current Assignee Address: US OH Cincinnati
- Agency: Frost Brown Todd LLC
- Main IPC: A61K31/40
- IPC: A61K31/40
Abstract:
Thalidomide analogs that modulate tumor necrosis factor alpha (TNFα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.
Public/Granted literature
- US20130035363A1 Thalidomide Analogs Public/Granted day:2013-02-07
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