Invention Grant
US08853258B2 C-linked hydroxamic acid derivatives useful as antibacterial agents
有权
用作抗菌剂的C-连接的异羟肟酸衍生物
- Patent Title: C-linked hydroxamic acid derivatives useful as antibacterial agents
- Patent Title (中): 用作抗菌剂的C-连接的异羟肟酸衍生物
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Application No.: US13501776Application Date: 2010-10-04
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Publication No.: US08853258B2Publication Date: 2014-10-07
- Inventor: Matthew Frank Brown , Anthony Marfat , Michael Joseph Melnick , Usa Reilly
- Applicant: Matthew Frank Brown , Anthony Marfat , Michael Joseph Melnick , Usa Reilly
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent John A. Wichtowski
- International Application: PCT/IB2010/054463 WO 20101004
- International Announcement: WO2011/045703 WO 20110421
- Main IPC: A61K31/382
- IPC: A61K31/382 ; A61K31/47 ; A61K31/661 ; C07D215/06 ; C07C317/44 ; C07D231/56 ; C07F9/12 ; C07C323/65 ; C07C317/46 ; C07D213/56 ; C07C317/48 ; C07D263/08 ; C07D295/03 ; C07D263/20 ; C07D335/02 ; C07D213/30
Abstract:
The present invention is directed to a new class of hydroxamic acid derivatives of Formula I, wherein the variables G, T, D, L, A, X, R1 and R2 are as described hereinabove, and their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.
Public/Granted literature
- US20120202777A1 C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents Public/Granted day:2012-08-09
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