Invention Grant
US08853280B2 Increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages
有权
增加烯丙胺药物化合物用于局部治疗皮肤和皮肤附属物的真菌感染的有效性
- Patent Title: Increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages
- Patent Title (中): 增加烯丙胺药物化合物用于局部治疗皮肤和皮肤附属物的真菌感染的有效性
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Application No.: US13252796Application Date: 2011-10-04
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Publication No.: US08853280B2Publication Date: 2014-10-07
- Inventor: Pichit Suvanprakorn , Panida Vayumhasuwan , Nardo Zaias
- Applicant: Pichit Suvanprakorn , Panida Vayumhasuwan , Nardo Zaias
- Applicant Address: TH
- Assignee: Biophile Corporation, Ltd.
- Current Assignee: Biophile Corporation, Ltd.
- Current Assignee Address: TH
- Agent Julia A. Grimes
- Main IPC: A61K31/137
- IPC: A61K31/137 ; A61K31/131
Abstract:
The present invention provides compositions comprising allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages. In some embodiments a positive charge and enhancers are used in the compositions to allow for increased penetration of the active ingredient through skin and skin appendages. In some embodiments the positively charged active ingredients are either dissolved in the vehicle directly or dissolved in a plurality of beads suspended in the vehicle. The present invention also provides methods for making compositions comprising an allylamine drug compound, and methods of using such compositions for the treatment of fungal infections of the skin and skin appendages.
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